Ultra-Marathon-Induced Increase in Serum Levels of Vitamin D Metabolites: A Double-Blind Randomized Controlled Trial. While an increasing number of studies occupies the importance of vitamin D for sporting performance, the impact of any kind of movement on the vitamin D metabolism is poorly characterized. We wanted to identify the reactions of some vitamin D metabolites on ultra-marathon runs.A design with repeated measurements has been implemented, in which 27 amateur runners have been divided into two groups: those who received a single dose of vitamin D3 (150'000 IE) for 24 hours before the start of the marathon (150,000 IE) and those (n = 14) which received a placebo. Blood samples were taken for 24 hours immediately after and 24 hours after the barrel.In both groups of runners, the serum levels 25 (OH) D3, 24.25 (OH) 2D3 and 3-EPI-25 (OH) D3 after the ultra-marathon increased significantly by 83%, 63% and 182% respectively. The increase was most pronounced in the vitamin D group.Body mass and fat mass decreased significantly after the barrel in both groups.
Ultra marathon induces the mobilization of vitamin D in the blood.In addition, the elevations of 24.25 (OH) 2d3 and 3-EPI-25 (OH) D3 mean that the load stimulates the vitamin D metabolism. The work can be found under https://pubmed.ncbi.nlm.nih.gov/33255807/