Exercise-Associated Hyponatremia During a Self-Paced Marathon Attempt in a 15-Year-Old Male Teenager The increased participation in endurance sports such as marathon runs has found scientific interest, especially in adult athletes. In a few studies, however, it was examined how a marathon has an effect on children and adolescents.The present case study had 2 objectives: first, the description of the pacing during a marathon and secondly the examination of the acute reactions of the blood physiological and biochemical parameters during the race (before and after the race) and at five consecutive days after the race. The participant was a 15-year-old boy, who completed a marathon attempt for the first time and ended in 5 h 19 m 53h. Positive pacing was observed (a running speed decreasing during the race) with a final spurt.An increase in fluid intake over the race has been shown.A stress-associated hyponatremia (eah, plasma sodium concentration <135 mmol / l) was found after the race.C-reactive protein (CRP) correlated neither with creatine kinase (CK) nor lactate dehydrogenase (LDH);However, leukocytes correlated very strongly with LDH, but not with CK.CK and LDH were almost perfect with creatinine correlated.In addition, the creatinine clearance correlated very strongly with CK, but not with LDH.Leukocytes, transaminases, LDH and CK turn off after the race from the physiological field, but return to normal values within the five-day recovery phase.
In summary, it can be said that a male teenager at the age of 15 years could complete a marathon without any significant health effects in less than 6 hours. He developed a mild and asymptomatic stress-associated hyponatremia and increased leukocytes, CRP, CK and LDH as markers for inflammation and damage to skeletal muscles. The stress-associated hyponatremia after the marathon was corrected within a day. The complete case report can be found under https://www.mdpi.com/1648-9144/55/3/63